Dr Ron Davis’s big immune study is looking at HLA genes. Here’s why.

Dr Ron Davis has won a large NIH (US National Institutes of Health) grant for an immunology project with a strong focus on HLA genes. Which may have led some to wonder, ‘What are they?’ HLA (human leukocyte antigen) molecules play a critical role in the immune system, particularly by activating T cells. There is …

Continue reading Dr Ron Davis’s big immune study is looking at HLA genes. Here’s why.

Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS

Guest blog by Professor Chris Ponting and colleagues. UK Biobank - a national biobank different from the ME/CFS biobank - has data from around 500,000 individuals, including both healthy people and those with one or more of the many different diseases in the UK population. About 2,000 people in the sample reported that they had …

Continue reading Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS

A plan to replicate Mark Davis’s remarkable findings of immune activation in ME/CFS

A team led by Edinburgh University’s Professor Chris Ponting has won funding for a PhD student who would follow up and expand on remarkable recent findings made at Stanford University, where Dr Mark Davis may have pinpointed a major issue in the immune system in ME/CFS. Last year, Davis produced strong evidence of T cell …

Continue reading A plan to replicate Mark Davis’s remarkable findings of immune activation in ME/CFS

A new research landscape emerges in America

Things are changing in the US for ME/CFS research as four new collaboratives set up and get to work. In September last year, the National Institutes of Health (NIH) announced $35 million of funding to establish three new ME/CFS research collaboratives and a supporting data centre. Since then, the Open Medicine Foundation (OMF) has helped …

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The CMRC embraces the biomedical

The CFS/ME Research Collaborative has belatedly recognised the critical importance of focusing on biomedical research to uncover the biological mechanisms behind ME/CFS. Its controversial deputy chair, Prof Esther Crawley, is standing down and will be replaced by biomedical researcher Prof Chris Ponting. The Collaborative has started taking concrete action to engage with patients and has also announced ambitious plans to enable much more biomedical research in the UK. [read more]