The best evidence yet that immune system problems can cause ME/CFS?

The best evidence yet that immune system problems can cause ME/CFS?

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Human leucocytes Antigen (HLA) proteins play an essential role in helping the immune system to recognise pathogens. This new research is easily the best study yet of HLA alleles (gene variants) in ME/CFS. It finds links between alleles of at least two HLA genes and ME/CFS. And since the illness can’t change (HLA) DNA, the link must be that the alleles must play a causal role in ME/CFS. So this evidence that the immune system plays a causal role for…

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(Not ME/CFS.) The coronavirus report behind the big shifts in policy by UK and US governments

(Not ME/CFS.) The coronavirus report behind the big shifts in policy by UK and US governments

Until very recently, the US and UK governments were taking a relatively gentle approach to controlling the new coronavirus epidemic – compared with most other governments around the world. A very recent report from UK academics shows that the strategy would probably have led to a huge number of deaths — well over a million in the US. The report is based on a detailed model using information from many sources. This blog explains how the model works, what it…

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Prof Leonard Jason
Leonard Jason research finds that many young people have ME/CFS

Leonard Jason research finds that many young people have ME/CFS

UPDATED: Feb 15.2.20 A new study finds that 0.75%, or 1 in 130 young people, have ME.CFS – a higher rate than for adults. Only 5% of the young people already had a diagnosis. Prevalence increased rapidly as children moved into adolescence. And ME/CFS appears to be more common among African-American and Hispanic young people than among whites. How do you find out how common an illness is when it is hard to diagnose, most doctors know little about it…

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Sign up! Your support could help win funding for a game-changing ME/CFS study

Sign up! Your support could help win funding for a game-changing ME/CFS study

Researchers and patients are about to submit an application to the UK’s two big medical research funders for a 20,000-patient genetic study. The team want people with ME to sign up to show funders that the community backs the study and that large numbers of people are ready to join it. Your action today could help the world’s largest ME/CFS genetics study win funding – and could make a huge difference for patients, helping to identify biological causes of the…

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Latest from Ron Davis: more evidence of “something in the blood”

Latest from Ron Davis: more evidence of “something in the blood”

More clues are pointing to a role for blood plasma in ME/CFS. Ron Davis recently presented data showing that ME/CFS cells behave normally in the nanoneedle test IF they are tested in healthy plasma. Also, red blood cells from ME/CFS patients are not as deformable as those from healthy people — but researchers only see the difference when patient’s cells are tested in their own plasma. Plus, a bigger and better pathogen hunt and another drug candidate emerges from nanoneedle…

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Stanford symposium: the potential of smartphones to better understand diseases, including ME/CFS

Stanford symposium: the potential of smartphones to better understand diseases, including ME/CFS

“We think smartphones will be the most important health tool in future”, said Dr Michael Snyder at the recent Stanford ME/CFS symposium. Snyder heads up the Stanford Centre for Genomics and Precision Medicine, as well as the Genetics Department at Stanford University. His presentation highlighted the potential of technologies to monitor health and better understand diseases – including ME/CFS. Snyder’s work on personal, data-driven medicine kicked off with a landmark paper in 2012 (which wasn’t covered in his talk). This…

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