Significant association of DNA variants with self-reported ME/CFS

Guest blog by Professor Chris Ponting and colleagues. SummaryA new analysis using data from UK Biobank indicates that one version of a particular gene increases the risk of ME/CFS in women. The gene codes for a transporter protein in the mitochondrial membrane and plays a critical role in the urea cycle, which is important for …

Continue reading Significant association of DNA variants with self-reported ME/CFS

Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS

Guest blog by Professor Chris Ponting and colleagues. UK Biobank - a national biobank different from the ME/CFS biobank - has data from around 500,000 individuals, including both healthy people and those with one or more of the many different diseases in the UK population. About 2,000 people in the sample reported that they had …

Continue reading Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS

A plan to replicate Mark Davis’s remarkable findings of immune activation in ME/CFS

A team led by Edinburgh University’s Professor Chris Ponting has won funding for a PhD student who would follow up and expand on remarkable recent findings made at Stanford University, where Dr Mark Davis may have pinpointed a major issue in the immune system in ME/CFS. Last year, Davis produced strong evidence of T cell …

Continue reading A plan to replicate Mark Davis’s remarkable findings of immune activation in ME/CFS